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Skin - Melanoma SACT Regimens

Avelumab Monotherapy

Regimen

Indication

00535a

Treatment of adult patients with metastatic Merkel cell carcinoma who have received 1 or more lines of chemotherapy for metastatic disease

Cemiplimab Therapy

Regimen

Indication

00812b

As monotherapy is indicated for the treatment of adult patients with metastatic or locally advanced cutaneous squamous cell carcinoma (mCSCC or laCSCC) who are not candidates for curative surgery or curative radiation

Cobimetinib and Vemurafenib Therapy

Regimen

Indication

00373a

Cobimetinib in combination with vemurafenib is indicated for the treatment of adult patients with unresectable or metastatic melanoma with a BRAF V600 mutation

Dabrafenib Monotherapy

Regimen

Indication

00237a

Treatment of adult patients with unresectable or metastatic melanoma with a BRAF V600 mutation

Dacarbazine Therapy

Regimen

Indication

00464a

Treatment of metastatic malignant melanoma.

Encorafenib and Binimetinib Therapy

Regimen

Indication

00563a

Treatment of adult patients with advanced (unresectable or metastatic) melanoma with a BRAF V600 mutation

Ipilimumab Monotherapy

Regimen

Indication

00105a

Treatment of advanced (unresectable or metastatic) melanoma in adults.

Nivolumab Monotherapy - 14 day

Regimen

Indication

00483a

As monotherapy for the treatment of advanced (unresectable or metastatic) melanoma in adults.

00483f

As monotherapy for the adjuvant treatment of adults with melanoma withinvolvement of lymph nodes or metastatic disease who have undergonecomplete resection

Nivolumab Monotherapy - 28 day

Regimen

Indication

00484a

As monotherapy for the treatment of advanced (unresectable or metastatic) melanoma in adults.

00484c

As monotherapy for the adjuvant treatment of adults with melanoma with
involvement of lymph nodes or metastatic disease who have undergone complete resection

Nivolumab 1mg/kg Ipilimumab 3mg/kg Therapy

Regimen

Indication

00431a

Nivolumab in combination with ipilimumab is indicated for the treatment of advanced (unresectable or metastatic) melanoma in adults

Nivolumab 3mg/kg Ipilimumab 1mg/kg Therapy

Regimen

Indication

00551b

Nivolumab in combination with ipilimumab is indicated for the treatment of advanced (unresectable or metastatic) melanoma in adults

Pembrolizumab 200mg Monotherapy

Regimen

Indication

00455b

As monotherapy for the treatment of adults with unresectable or advanced melanoma

00455c

For the treatment of ipiplimumab-refractory patients with unresectable or advanced metastatic melanoma.

00455g

As monotherapy is indicated for the adjuvant treatment of adults with Stage III melanoma and lymph node involvement who have undergone complete resection

00455l

As monotherapy for the adjuvant treatment of adults with Stage IIB or IIC melanoma and who have undergone complete resection.

Pembrolizumab 400 mg Monotherapy

Regimen

Indication

00558b

As monotherapy for the treatment of adults with unresectable or advanced melanoma

00558c

For the treatment of ipilimumab-refractory patients with unresectable or advanced metastatic melanoma

00558g

As monotherapy is indicated for the adjuvant treatment of adults with Stage III melanoma and lymph node involvement who have undergone complete resection

00558l

As monotherapy for the adjuvant treatment of adults with Stage IIB or IIC melanoma and who have undergone complete resection.

Trametinib and Dabrafenib Therapy

Regimen

Indication

00415a

Trametinib in combination with dabrafenib is indicated for the treatment of adult patients with unresectable or metastatic melanoma with a BRAF V600 mutation

Vemurafenib Monotherapy

Regimen

Indication

00102a

Treatment of adult patients with BRAF V600 mutation-positive unresectable or metastatic melanoma

Vismodegib Monotherapy

Regimen

Indication

00236a

Treatment of adult patients with symptomatic metastatic basal cell carcinoma (MBCC)

00236b

Treatment of adult patients with local advanced basal cell carcinoma inappropriate for surgery or radiotherapy.