Skip to main content

Warning notification:Warning

Unfortunately, you are using an outdated browser. Please, upgrade your browser to improve your experience with HSE. The list of supported browsers:

  1. Chrome
  2. Edge
  3. FireFox
  4. Opera
  5. Safari

Paediatric SACT Regimens

Dinutuximab beta and Isotretinoin Therapy

Regimen

P00548a

For the treatment of high-risk neuroblastoma in patients aged 12 months and above, who have previously received induction chemotherapy and achieved at least a partial response, followed by myeloablative therapy and stem cell transplantation, as well as patients with history of relapsed or refractory neuroblastoma, with or without residual disease. Prior to the treatment of relapsed neuroblastoma, any actively progressing disease should be stabilised by other suitable measures.

Blinatumomab Paediatric Therapy

Regimen

P00567a

As monotherapy for the treatment of paediatric patients aged 1 year or older with Philadelphia chromosome negative CD19 positive B-cell precursor ALL which is refractory or in relapse after receiving at least two prior therapies or in relapse after receiving prior allogeneic hematopoietic stem cell

Blinatumomab for Relapsed Paediatric ALL: Consolidation Therapy

Regimen

P00707a

As monotherapy for the treatment of paediatric patients aged 1 year or older with high-risk first relapsed Philadelphia chromosome negative CD19 positive B-precursor acute lymphoblastic leukaemia (ALL) as part of the consolidation therapy.

Pembrolizumab Paediatric Monotherapy

Regimen

P00711a

As monotherapy for the treatment of paediatric patients aged 3 years and older with relapsed or refractory (R/R) classical Hodgkin lymphoma (cHL) who have failed autologous stem cell transplant (ASCT) or following at least two prior therapies when ASCT is not a treatment option

P00711b

As monotherapy for the adjuvant treatment of adolescents aged 12 years

and older with Stage IIB or IIC melanoma and who have undergone

complete resection.