The HSE National Cancer Control Programme develops national Systemic Anti-Cancer Therapy (SACT) Regimens to support safe, evidence-based and cost-effective cancer treatment for all Irish cancer patients. These regimens are developed under the guidance of Medical Consultants involved in the treatment of patients with cancer with input from nursing staff, pharmacists and other healthcare professionals. These regimens underpin the National Cancer Information System (NCIS) and include specific indications for specific drugs. They do not direct care in the same manner as clinical practice guidelines.
The list of regimens contained on the website is not comprehensive; additional regimens will be added to this site over time. Please email any comments or feedback on these regimens to oncologydrugs@cancercontrol.ie.
For information on open clinical trials please refer to the Cancer Trials Ireland website and also to basket trials.
Oral Anti-Cancer Medicines and their associated regimens is available below.
Supportive Care
- Classification Document for Systemic Anti-Cancer Therapy (SACT) Induced Nausea and Vomiting (PDF, 468 KB, 14 pages)
- Antiemetic Medicines for inclusion in NCIS (Medical Oncology) (PDF, 221 KB, 6 pages)
- Antiemetic Medicines for Inclusion in National Cancer Information System (NCIS) - Haemato- Oncology (PDF, 357 KB, 21 pages)
Current regimens for a range of tumour groups are available - please choose from the following tumour groups:
Breast SACT regimens (Neoadjuvant/ Adjuvant Treatments)
Breast SACT Regimens - Locally Advanced / Metastatic
Gastro-intestinal SACT Regimens
Leukaemia and Myeloid Neoplasms SACT Regimens
Lymphoma and Other Lymphoproliferative Disorders SACT Regimens
Plasma Cell Disorders SACT Regimens